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    Smallpox vaccine, the first successful vaccine to be developed, was introduced by Edward Jenner in 1796. He followed up his observation that milkmaids who had previously caught cowpox did not later catch smallpox by showing that inoculated cowpox protected against inoculated smallpox.

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    Edward Jenner had promised that vaccination would wipe out instead, all other diseases, even the most persistent and deadly more rapidly without any serums than did smallpox with its repeated vaccinations.

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